Volume 5 · Issue 1

Research

Identification of a New Site of Metabolism for Phenprocoumon by modeling its CYP2C9 hydroxylation Pattern

Molecular modeling conducted to study the observed sites of metabolism for cytochrome P450 enzyme CYP2C9 and find a hitherto unknown hydroxylation site for phenprocoumon. Four hydr…

Research Article

CCK2-Gastrin Antagonist: Development of PNB-001 (4-Chloro-5-Hydroxy-1-Phenylethyl-5-Phenyl-1, 5-Dihydro-Pyrrol-2-one) as Anti-Inflammatory Analgesic

To prepare and evaluate CCK gastrin antagonists from readily available materials such as furfural and to focus on inflammatory pain management.…

Research

Profile Characterization of Volatile Organic Compounds on in vitro Propagated Plants of Clinopodium odorum and it’s Comparison with the Wild Plant

The aim of this work was to study the effect of the in vitro culture conditions of plants of Clinopodium odorum on the production of volatile organic compounds (VOCs), and to ident…